Top pharmaceutical products by sales worldwide 2018

Top 15 pharmaceutical products by sales worldwide in 2018 (in million U.S. dollars)

by Matej Mikulic, last edited Aug 9, 2019
Top pharmaceutical products by sales worldwide 2018 Similar to the years before, U.S. company AbbVie’s Humira maintained its place as the global top ranked drug based on revenue. During 2018, Humira generated a huge 20 billion U.S. dollars in revenue, another significant increase from 18.4 billion dollars the year before. The second ranked drug Eliquis, marketed by Bristol-Myers Squibb and Pfizer, made less than half of Humira’s revenue. Celgene’s Revlimid completed the top ranked three pharmaceutical products worldwide.
Top drug Humira

Humira is used mostly for the treatment of rheumatoid and psoriatic arthritis. However, like many other top drugs, the range of medical conditions it can be used to treat is much larger. Thus, the drug is also used to treat Crohn’s disease, ankylosing spondylitis, ulcerative colitis, psoriasis, uveitis, and some other autoimmune diseases. Humira is administered subcutaneously via injection. It was approved for the first time in 2002 in the United States.

Blockbuster drug reliance

Blockbuster drugs often have a large impact on the manufacturer. In some cases, pharmaceutical companies are highly dependent on their sales performance. In the case of Humira, AbbVie generates over 60 percent of its total revenue from this drug and almost 80 percent from its top 3 products. Companies that depend on a small number of blockbuster drugs could be under threat of heavy revenue loss. Biosimilars of Humira (adalimumab) are already available and will take more and more of the market in the years to come. Thus, it is not expected that Humira will exceed the 20 billion-dollar-revenue mark but will more likely suffer from a distinct revenue decrease until 2024.
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Top 15 pharmaceutical products by sales worldwide in 2018 (in million U.S. dollars)

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