Number of cancer cases probably caused by HPV by gender U.S. 2016-2020

From 2016 to 2020, there were around 25,689 cases of cancers associated with HPV per year among females, with around 21,500 of these cases probably caused by HPV. This statistic depicts the number of cancer cases in the U.S. that were probably caused by HPV per year from 2016 to 2020, by gender.

Number of select cancer cases that were probably caused by HPV in the U.S. per year from 2016 to 2020, by gender*

Characteristic	Average number of yearly cases of HPV-associated cancers	Number of cases probably caused by HPV
Total	46,711	37,000
Female	25,689	21,500
Male	21,022	15,500

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Release date

September 2023

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Region

United States

Survey time period

2016 to 2020

Supplementary notes

* HPV-related cancers affect parts of the body that include the cervix, vagina, vulva, penis, anus, rectum, and oropharynx (back of the throat, including the base of the tongue and tonsils).

To determine the cancers most likely to be HPV-associated, the following additional criteria were applied to the NPCR/SEER data— All cancers were confirmed microscopically. Cervical cancers were limited by histology to carcinomas only (ICD-O-3 histology codes 8010 to 8671 and 8940 to 8941). All other cancer sites were limited by histology to squamous cell carcinomas only (ICD-O-3 histology codes 8050 to 8084 and 8120 to 8131). Oropharyngeal cancers were defined as having the following ICD-O-3 site codes: 19, 24, 28, 51, 52, 90, 91, 98, 99, 100, 101, 102, 103, 104, 108, 109, 140, 142, and 148.

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